I don't know about Estroven, but I was having hot flashes day and night about 4 times an hour. I found out that for me, quitting the coffee drinking and taking melatonin at bedtime worked for me. I was out of town for a few days, and wanted to get a good night's sleep, therefore, abstained from coffee and took the melatonin. Haven't had a hotflash since. ... View related article.