If you have a ceramic toothbrush holder with holes at the top for your toothbrushes, it can trap "gunk" at the bottom. Most of these holders have a little plug that you can take out to clean it. To keep germs down, poke an antibacterial wipe down into the holder to rest at the bottom. Drips will land on the wipe, and you can just take out the plug to remove it when you are cleaning your bathroom. No more disgusting gunk will accumulate.
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Here are questions related to Cleaning a Toothbrush Holder.
I have a vertical plastic toothbrush holder that cannot be opened. How do I clean the toothpaste residue on the bottom of it? I was thinking of filling it partially with water, through the toothbrush holes and putting a "substance" in it, ie: broken Polident tablets, distilled white vinegar, etc. Please help. Thanks.