It would be best to check with the manufacturer or your machine. Computers are made to be left on for long periods of time but there is probably a recommendation for your model. Mine works best if left on all the time, is energy efficient and has a sleep mode. Some models may use a lot of power or you may want to turn off your monitor as I believe it uses the most energy.
I generally leave my computer on in the "sleep mode" since we check the e-mail several times a day, plus will be using the computer during the day. If you use your computer only once a day ... turn it off when finished. Tip: When you leave the house always turn off your computer.
#2 We leave our computer on all the time and there hasn't been a problem. It seems to me that there would be more wear and tear on the computer by turning it on and off all the time.
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