With cold and flu season coming along make sure to replace everyone's toothbrush after a bout of cold or something. (not overly frugal to keep replacing a toothbrush, but that is still cheaper then ongoing Dr. bills) some people say to just boil the toothbrushes also.
I always stick my toothbrushes and mouth rinse cup in the dishwasher everytime I run it. This way I make sure it all gets sanitized at least 2-3 times a week.
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