Fusible interfacing is generally thinner than the fleece and is used to add weight, stability and durability to a pattern piece. Interfacing is generally used in collars, waistbands and where buttons are so that buttons or the buttonholes don't tear the fabric. Fusible fleece is not something I have used much but it is thicker and can be used as the middle layer of a quilted item. Both are ironed in place and can be cut with scissors and/or a rotary cutter.
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