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I also do this for any mouth appliance, such as retainers, night splints. But I take their holder, pour in the listerine, let set for 10 minutes. Can be done with vinegar too, but listerine tastes much better!
Be compliant with this especially when colds are in the house hold. Sore throats should warrant this a couple times a day. Strep, toss out the brushes. People don't think about germ "retainers" such as their toothbrushes.
I do something like this, I pour Listerine on the toothbrush, so that it sinks into the hard-to-spritz places.
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