Awhile ago I read a recipe that really worked great for set in stains. It had ammonia and other items. One thing I remember about this recipe is your clothes had to soak a few days. Thanks so much to anybody that has this recipe.
I don't know what type of fabric you are working with, so proceed carefully with this. I have used a paste made from powdered Cascade, lemon scent (just a little water with the powder to make a paste). Apply to stain, and then wash in the hottest water allowable for fabric. This works great on removing "rust" stains from old dresser scarves/runners.
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Seems like I remember someone submitting a stain remover that even works on old stains. I bought a new purple blouse. I got something on it and sprayed spay and wash on it and it didn't touch it.
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