Some detergent will work, make sure it has no bleach in it. You need to get them house trained better. Also letting them out in the garden before bedtime will help them keep through the night.
Your first line of defense is to ban the dog from the bathroom. Beyond that, you will need to first be certain that the floor is clean and the area "nuetralized". We swear by Nature's Miracle. ( be sure to follow directions) Strong cleaners with any type of ammonia will just reinforce the desire. Oxyclean does a great job. Once clean, you will need to limit your dog's ability to visit your bathroom. For him, it is like finding that favorite spot outside to pee. One more thing you can try is to put well-worn (smelly) t-shirts of your family's down on the spot. This will also help deter the desire to elminate there. Best wishes!

My dog pees in the house at night, only when we're asleep, and only on a rug (but never in our bedroom where there is wall-to-wall carpeting). I have discovered she often does this only an hour or two after we gave her a walk and then went to bed, so it's not likely to be a full bladder.
She is a 2 year old terrier/mix we got last January from a shelter. We closed off the living room at night, but then she peed on the runner rug in the dining room, so we temporarily removed that. Then she peed on the bathroom rug, so we removed that. Any idea what's going on, or how to fix it?
Mark from Alameda, CA
Our daughter adopted a Collie from the shelter and didn't listen to me about crate training. Several accidents and chewed up shoes later she decided to give it a try. Her dog is much calmer and we don't have to worry about her ransacking the house at night when we are all asleep. (12/07/2005)
By Irish
By CEIL
By Topo Gigio
By ThriftyFun
By Vic
It takes 2 weeks or less of sincere diligence on your part to train a dog not to pee in the house. It would take you longer than that to get the dog used to the crate, if ever. And all the time that she is in a crate is totally wasted training time, wasted dog/human interaction time and as I have said even more stressful for the dogs. All due respect for the rescue person who is making the best of a difficult situation.
For people who say how their dog loves to go in his crate, it's because he feels safest there now. Humans always have the upper hand, because they are bigger, but communication, diligence and mutual trust are a lot more effective in raising a well adjusted socialized dog.
And I am pleased that you ask first "what's going on?", which is a lot more revealing of your inner character than "how do I fix it?". It shows that you actually care about what's going on with the dog rather than just how to mold it into something you want without considering the dog's needs.
It could be that she has been pad trained and is using the small rugs, because they are the closest thing to what she recalls. She has had a life for 2 years that you may know very little about.
Is she sleeping with you, or in the bedroom? You could consider closing the bedroom door at night. Put some attention on house training again, mostly in the area of enormous praise and lovins when she does go potty so that she will choose to hold it just so that she can get that loving praise from you for going outside.
We can't always be sure if a dog's bladder is full or not. Sometimes we feel the urge to go even if we have only been an hour ago. And it might also be a UTI issue.
If the pad training or even small rug training is something that has been pushed on her by a previous owner who wasn't considering the dog's needs, it may be something that you may choose to accept and give her her own rug, considering that it's better than her choosing a wall to wall carpet. (07/13/2007)
By Sheraone
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