Oh lord, please do not use Goof Off- Goo Gone on your clothes. That is a oil based product similar to WD-40 and yes,it might take paint out but you will then be left with a big oil/grease stain to try and remove. Go on-line to Red Devil Paint.com and get a small bag of "Save a Brush". This is the only thing I have ever used that actually will take dried paint out of material. It was first sold to professional painters to remove any paint from their very expensive paint brushes and painters over-alls. Back then people did not throw away their tools/clothes.
They had one pair and had to take care of them. That was something my great grandfather and grandfather used and is still made today. Very inexpensive also. Get it at ,"Red Devil Paint Company.com" Do not use an oil based product they do not work.
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If it is a latex paint, try Goof Off or Goo Gone. They are both latex paint removers that can get paint spots off carpet and clothing. I would try applying the solution to a cloth first, then rub it on the spots that have the paint on them. It should loosen it enough to where it can be removed. (11/28/2009)
I haven't tried this on clothes, but had great success on the carpet with dried on gloss paint. Spray with hair spray (lacquer) and leave for 5 seconds or so and then rub off with a damp cloth. Good luck. (11/30/2009)
I don't think you can do this. I've learned the hard way to have a painting outfit. So I have a pair of my husband's old pants and a raggedy shirt that is splattered with white primer and then gold and mauve paint. If you don't have really old clothes, it's time to visit the thrift store. (06/16/2010)
Try soaking it in white vinegar. (Just the spot). White vinegar will remove completely dried paint off paintbrushes, there is no reason to think it won't work on clothes. Essentially it is ruined anyway, unless you get the paint off, I don't think you have anything to lose in trying. (08/06/2010)