Can Immunizations Cause a Positive Parvo Test?

Husky puppy getting a vaccine.
According to the ASPCA "some immunologists believe the vaccine antigen should not generate a positive result at all while others believe the weak positive is a true positive. However, a positive test accompanied by clinical signs, a low white blood cell count or history of exposure to parvovirus should be interpreted as positive regardless of vaccination." This page contains discussions regarding the question, "Can immunizations cause a positive parvo test?".


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August 24, 2017

We recently bought a Bulldog puppy from a breeder for one thousand dollars. We had him for 3 days and then noticed he was throwing up and he wouldn't eat or drink. I panicked because I had a dog years ago that died of parvo. Can Immunizations Cause a Positive Parvo Test?


I rushed my puppy to the vet because he continued throwing up, but it was just dry heaves. There was no diarrhea or fever. He was 10 weeks old and had his first set of shots the breeder told us. The vet wanted to rule out parvo just in case. The results were in immediately and it came back a weak positive.

I am sick to my stomach because I may have put down a healthy puppy that may have just had a stomach bug. We couldn't afford the treatment that would have cost us $4,000 dollars. I didn't want to take him home and try to treat him myself because I couldn't stand to see him suffer! Could the positive parvo test have been because of immunizations?


Gold Feedback Medal for All Time! 949 Feedbacks
August 25, 20170 found this helpful
Best Answer

It seems your biggest concern is not who is responsible (money) but did your new puppy have Parvo and/or did you put down a puppy that was just sick.


Your question: can immunizations cause a positive Parvo test?
The answer (from a highly respected vet and papers on numerous tests) is NO - that does not happen (previous tests papers in the 1990s did say they could). New reports all say the SNAP test is very reliable. Here is a partial statement:

It was indicated before that the SNAP Parvo Test may cross-react 415 days postvaccination. Why is the information different now?
The information we derived from studies performed in the
1990s did indicate that there may be a potential interference
with vaccinated canines 415 days postvaccination with
other available assays. However, this University of Wisconsin
study has shown that the SNAP Parvo Test does not detect
CPV-2 (Parvo), in canine feces after vaccination.
If the vet gave a SNAP test then your puppy must have had Parvo so now you may wish to concentrate on reporting this to the seller as they may not be aware of this and are still selling puppies that may been exposed to Parvo. You should be able to have your money refunded with a copy of the report from the



Note: Please be aware that your house (car?) or anywhere your puppy was is nor contaminated so be sure to check out what needs to be done before you can bring in another puppy. I would suggest a new puppy be completed all vaccinations (20 weeks?) before bringing them home.

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Gold Post Medal for All Time! 677 Posts
August 24, 20170 found this helpful

Usually not. I would sue the seller of the dog and have him pay the expenses.

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Bronze Post Medal for All Time! 105 Posts
August 24, 20170 found this helpful

If the puppy is 10 weeks old it isn't possible the breeder fulfilled their obligation to vaccinate the dog before selling them. Here in Tahiti they start the vaccinations at 6 weeks. This is a series of 4 sets of shots given 2 weeks apart from each other. This would mean your dog should of been 14 weeks old before they sold him to you.


For the amount of money you paid for this dog he should of come with all his shot certificates, papers, and the documents of the breeder.
If I were you I would take this person to small claims and sue them for the cost of the dog. I would also report the breeder to the board. People who breed dogs for a living needs the papers and certificates to do this. Maybe this breeder has been reported before and they can close down this establishment if this is the case.
I am so sorry to hear about you putting the dog down. I know one of the vaccinations they give at first is for parvo. I have 3 small puppies right now and I am going through the series of vaccinations on them. I have completed 3 of the 4 series of vaccinations so far. I have one more to go.

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Diamond Post Medal for All Time! 1,246 Posts
August 25, 20170 found this helpful

I'm so sorry this happened to you. I would think the seller is responsible for this. It's hard to tell what caused any of the illness.. but this isn't right.

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